Bioss Inc.'s HPS2 Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen. The HPS2 Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated was generated using AP3B1 as the antigen and it reacts with Human, Mouse, and Xenopus/Amphibian.
Description
Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles